COVID-19: step-by-step treatment strategies

Objective: to evaluate the effectiveness and safety of anticoagulant glucocorticosteroid therapy in patients with COVID-19, determine step-by-step solutions prescription drug at inpatient stage. Materials methods. We performed two randomized continuous prospective comparative studies including 1,801 diagnosed COVID-19 pneumonia who were undergoing treatment November-December 2020 (1,004 patients) Gomel Regional Clinical Hospital for Disabled World War II February 2021 (797 City No. 3. Results. The strategy treating associated is divide into groups high moderate risks adverse outcomes (based on developed predictors) first day hospitalization. In moderate-risk patients, “protocol” stabilizes condition; high-risk it not effective. Early preemptive (ACT) individual hormone (prior pulse therapy) may stabilize condition increase survival rate from 82.1 % 96.8 %, p = 0.0001. additional steps are: targeted use tocilizumab Somatic Department before Intensive Care (70 survival, 0.031), oxygen therapy, pronposition, catheterization domestic hepatoprotector, membrane-stabilizing antiischemic “Thiotriazoline” blood lactate levels (lactate dehydrogenase (LDH)), which metabolic processes affected organs (in dynamics by 342.7 ± 92.8 units/l 5 days compared control group, p=0.0001). When patient’s gets stabilized, respiratory physical rehabilitation are final recovery Conclusion . Therapeutic combination thiotriazoline some being a risk have led an increased — hospital stage,